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Telomeres are short bits of specialized DNA that cap the chromosomes, which tell a cell what to do. Over time, cells divide over and over to keep the body alive.

• Dr. Eric Li's blog
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Blue zone is a new book about places around the world where people achieve extraordinary longevity.  Watch

• Dr. Ping's blog
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Watch the video Dr. Ping talking with Dr. Tranquility on Be Well TV.

• YoungBodyMind's blog
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 I had the honor to present during the China Anti-aging conference to a broad spectrum of scientists and practitioners - introducing our state of the art anti-aging program, YBM Life!  The reception was very warm and welcoming.  

I'd like to make the presentation available to www.youngbodymind.com members.  You may read the presentation by clicking this link.

• Dr. Eric Li's blog
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Many of us know that heart attack can come suddenly without warning.  Therefore a routine checkup is necessary to understand the risk.  However, there're not many tests that are credibly

• Dr. Ping's blog
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The mainstream media and belief is that alternative medicine such as Traditional Chinese Medicine, most of them thousands of years old, are not based on sciences, rather they are based on trial and error without rigorous scientific experiments to verify the validity.

I submit here that time proven medicines are indeed sciences if they can survive for thousands of years.

In applied mathematics and statistics, as I studied in Harvard, there're two types of statistical averages, the ensemble average and the time average.  Both can be statistically significant. 

Ensemble average is to observe an phenomena (e.g., an experiment) over many times (or objects) - the very base of scientific research.  For example, if you want to proven the effecacy of a drug, you design an experiment, and apply the drug to a number of rats or human (e.g., 300) for a few months, calculate the average results and draw conclusion. 

On the other hand, time average is to apply this drug only on a single person at a time.  When this person is not availabe, apply to another (again only one person).  If you do this over many many years, you will get identical results as the ensemble average, if both experiments are designed correctly.

In mathematical terms, if a1, a2, ..., an are the measurements for the n rats or people during a fixed period, then the ensemble average EA = (a₁ + a₂ + ...+a_n)/n.  If b(t₁), b(t₂), b(t₃), ..., b(t_n) are the measurements oberserved sequentially during a long period time, t₁<t₂<t₃<...<t_n, then, time average TA = [b(t₁)+b(t₂)+...+b(t_n)]/t_n.  As n goes to infinity, EA = TA.

This means

• Dr. Eric Li's blog
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As man ages, one of the first sign is an increase of estrogen and an increase of sex hormone binding globulin (SHBG). This, even without reduced total testosterone level, will change the key ratio/balance of testosterone/estrogen. It's a known scientific fact that this is the start of andropause - a steady process of male hormone decline and out of balance, a major cause of aging. (Read more YBM Hormone)   When this happens, instead of immediately jumping into bio-identical hormone replacement therapy, a herbal approach should be first tried. This includes reducing estrogen conversion, blocking estrogen receptors, reducing DHT conversion, and stimulating testosterone production.   An effective tool for reducing the estrogen effect is a high concentration extraction from cruciferous vegetables (broccoli, cauliflower, Brussels sprouts) of key ingradients, such as indole-3-carbinol (I3C), DIM (diindolymethane), ascorbigin, sulphoraphine, indoles, isothiocynates and glucosinolates. Animal studies have shown that the cruciferous vegetable extract modulates estrogen hormones by favorably changing the ratio of protective 2-hydroxyestrone versus the damaging 16-hydroxyestrone. Indole-3-carbinol also induces phase I and II detoxifying enzymes that can help neutralize estrogen metabolites and xenobiotic estrogen-like environmental chemicals. Human studies support the beneficial role of I3C in positively altering estrogen metabolism. Di-indoyl-methane (DIM), a phytonutrient found in cruciferous vegetables, has been shown in animal studies to help maintain normal levels of a potentially damaging estrogen called 4-hydroxyestrone.

• Dr. Eric Li's blog
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Leading authorities are advocating red yeast rice as an effective way to lower cholesterol (e.g., this article on WebMD), despite the fact that the primary ingredient in these red yeast rice supplements, lovastatin, is also the active pharmaceutical ingredient in prescription drugs for high cholesterol such as Mevacor, Lipitor, Zocor, and Statins. In fact, lovastatin was originally derived from another type of red yeast called Monascus ruber (read this article). For these prescription drugs, there have been many known side effects such as liver damage during long term use. For extensive drug side effect, review this article. Therefore, 1. Don't take "expert" advice for granted. Make your own research because in the end, it's your body which takes these drug or natural supplements in, not the experts'. 2. "Natural" does not mean "food". 3. Always take the lifestyle change approach to fix your issues if you can. Go to drugs or potent natural supplements when you have to, knowing the side effects.

• Dr. BT's blog
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