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Dr. Eric Li 的blog
由 Dr. Eric Li 于 周三, 2008-12-03 08:21 提交。
In the new book, Testosterone for Life, Harvard Doctor, Abraham Morgentaler, wrote about the myth of testosterone replacement and prostate cancer. It is a landmark book detailing the history of scientific discovery and the implication to male hormone replacement. Below is a summary of my reading of the book:
Early in this century, Dr. Charles Huggins' Nobel prize winning experiments showed that castration or injection of estrogen can cure or prevent prostate cancer. Since that time, the standard education of medicine has been that testosterone is bad for the prostate. Therefore, male hormone replacement therapy can be risky.
After over 65 years, recently, new scientific discover has shown just the opposite: 1. Low blood levels of testosterone do not protect against prostate cancer, and actually may increase the risk. 2. High testosterone level do not increase the risk of prostate cancer. 3. HRT does not increase the risk even among men who are already at high risk of prostate cancer. 4. For men who have prostate cancer, and are given drugs to drop their testosterone level to near zero, administrating testosterone might increase the risk of residual cancer to start to grow.
The reason to completely overturn the old Nobel prize winning theory is due to the incomplete statistical significance of the original experiments, thus drawing the wrong conclusion.
One very important concept, uniquely to YBM Hormone protocol, still ignored by most physicians and hormone doctors, including Dr. Morgentaler's analysis, is that hormone levels are very individual dependent. Good statistics can give good generalized results. However, when giving hormone replacement therapy to an individual, it's a totally different matter.
Take for example, the medical lab reference of testosterone normal range is 260-1000 ng/dL. Is a person who have 390 ng/dL low T? Not necessarily. Some people has 390 level even when they are in their early 20's, sexual, healthy, and manly. If this is the case, suplementing testosterone way beyond his own "normal" is dangerously breaking his own hormonal balance.
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